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• In addition, the info obtainable in the literature does not account for the steroid type or dose, as neither may be recognized.

Moreover, a element of endothelial dysfunction has been proposed, which can contribute to abnormal vessel reactivity. However, testosterone in physiologic doses could even be helpful in patients with angina , have greater ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood flow in males with established coronary artery illness . Therefore, an interplay of endogenous components of the patient’s danger profile in addition to the testosterone dosing could additionally be problems with whether or not opposed occasions occur.

Anabolic Steroids, Acute Myocardial Infarction And Polycythemia: A Case Report And Evaluate Of The Literature

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Case Report

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Rhoden EL, Morgentaler A. Risks of testosterone-replacement remedy and suggestions for monitoring. Testosterone alternative in hypogonadal men with angina improves ischaemic threshold and high quality of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone enhance human platelet thromboxane A2 receptor density and aggregation responses.

We report a case of an acute ST-segment elevation myocardial infarction in a affected person with traditional cardiac risk components using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, probably secondary to high-dose testosterone. The patient underwent profitable percutaneous intervention of the best coronary artery. Physicians and patients ought to be conscious of the clinical consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).